Dr Reka Toth

Research interests

Plant developmental biology


I’m interested in studying how developmental processes are regulated at cellular level by endogenous and exogenous signals.

Currently I’m studying the first formative division of liverwort Marchantia polymorpha, an emerging plant model system for evolutionary biology. I would like to understand how a unicellular spore gives rise to two cells with different cell fates by asymmetric cell division.

Using genetic and cell biology tools I aim to address the following questions:

  • what are the cellular processes of asymmetric cell division in Marchantia spores?
  • what are the major molecular components of the cell fate determination in Marchantia spores?
  • evolutionary conservation of asymmetric cell division between divergent plant linages?

Contact details


+44 (0) 1865 2750103


de Montaigu A., Giakountis A., Tóth R., Cremer F., Sokolova V., Porri A., Reymond M., and Coupland G. (2015) Natural diversity in the diurnal waveform of GIGANTEA expression impacts on Arabidopsis growth. PNAS,112:905-10.

Berns MC., Nordström K., Cremer F., Tóth R.,  Hartke M., Simon S., Klasen  J.R., Bürstel  I., Coupland G. (2014) Evening expression of Arabidopsis GIGANTEA is controlled by combinatorial interactions among evolutionarily conserved regulatory motifs.  Plant Cell, 26:3999-4018.

Terecskei K.#, Tóth R.#, Gyula P., Kevei E., Bindics J., Coupland G., Nagy F., Kozma-Bognár L. (2013) The circadian clock-associated small GTPase LIGHT INSENSITIVE PERIOD1 suppresses light-controlled endoreplication and affects tolerance to salt stress in Arabidopsis. Plant Physiology, 161:278-90.  (# shared first authors)

Tóth R.*, Gerding-Reimers C., Deeks, MJ., Menninger S., Gallegos RM., Tonaco IA., Hübel K., Hussey PJ., Waldmann H., Coupland G*. (2012) Prieurianin/endosidin 1 is an actin-stabilizing small molecule identified from a chemical genetic screen for circadian clock effectors in Arabidopsis thaliana. Plant Journal, 71:338-52. (* shared corresponding authors)

MacLean MA., Sugio A., Makarova OV., Findlay KC., Grieve VM., Tóth R., Nicolaisen M., Hogenhout SA. (2011) Phytoplasma effector SAP54 induces indeterminate leaf-like flower development in Arabidopsis plants. Plant Physiology, 157:831-41.

Kolmos E., Herrero E., Bujdoso N., Millar AJ., Tóth R., Gyula P., Nagy F., Davis SJ. (2011) Hypomorphic genetics supports a repressive role for EARLY FLOWERING 3 in the circadian clock. Plant Cell, 23:3230-46.

de Montaigu A., Tóth R., Coupland G. (2011) Plant development goes like clockwork. Trends in Genetics, 26:296-306.

Tóth R. * and Van der Hoorn RAL. (2010) Emerging principles in plant chemical genetics. Trends in Plant Science, 15:81-8;  *corresponding author

Kevei E., Gyula P., Fehér B., Tóth R., Viczian A., Kircher S., Rea D., Dorjgotov D., Schäfer E., Millar AJ., Kozma-Bognar L. and Nagy F. (2007) Arabidopsis thaliana circadian clock is regulated by the small GTPase LIP1. Current Biology, 17:1456-1464.

Kevei E., Gyula P., Hall A., Kozma-Bognár L., Kim W-Y., Eriksson M.E., Tóth R., Hanano S., Fehér B., Southern MM., Basto, RM., Viczián A., Hibberd V., Davis SJ., Somers DE., Nagy F. and Millar AJ. (2006) Forward genetic analysis of the circadian clock separates the multiple functions of ZEITLUPE. Plant Physiology, 140:933-945.

Hiltbrunner A., Viczián A., Bury E., Tscheuschler A., Kircher S., Tóth R., Honsberger A., Nagy F., Fankhauser C. and Schäfer E. (2005) Nuclear accumulation of the phytochrome A photoreceptor requires FHY1. Current Biology, 15:2125-2130.

Dodd A.N., Salathia N., Hall A., Kevei E., Tóth R., Nagy F., Hibberd JM., Millar AJ., Webb AAR.(2005) Plant circadian clocks increase photosynthesis, growth, survival, and competitive advantage. Science, 309:630-633.

Hall A., Kozma-Bognár L., Tóth R., Nagy F., Millar AJ. (2001) Conditional circadian regulation of phytochrome A gene expression. Plant Physiology, 127:1808-1818.

Tóth R., Kevei E., Hall A., Millar AJ., Nagy F., Kozma-Bogná, L. (2001) Circadian clock-regulated expression of phytochrome and cryptochrome genes in Arabidopsis. Plant Physiology, 127:1607-1616.

Kim L., Kircher S., Tóth R., Ádam É., Schäfer E., Nagy F. (2000) Light-induced nuclear import of phytochrome-A:GFP fusion proteins is differentially regulated in transgenic tobacco and Arabidopsis. Plant Journal, 22:125-33. 


List of site pages